View source for Phospholipids and Sphingolipids of Milk

=Objective=

To create a technology landscape report on '''Phospholipids and Sphingolipids of Milk'''<

:* Identify market players with prolific IP activity in the technology area
:* Segment the players by the industry they belong to<br/>
<br/>

'''Note''': ''This report is just a template and gives an indication of what the paid report contains.''<br/>
''[https://dolcera.net/teamwiki_prod/index.php/Template-_Phospholipids_and_Sphingolipids_of_Milk#Purchase_Information Click here] for information to purchase the report''


=Background=
==Introduction==
[[Image:MFGM_STR.gif|thumb|right|250px|[http://digitalcommons.calpoly.edu/cgi/viewcontent.cgi?article=1050&context=dsci_fac&sei-redir=1#search=%22sphingolipids%20milk%20fat%20globule%20membrane%22 MFGM_Str]]]

'''MFGM''': Milk fat globule membrane (MFGM) is a protein-lipid biopolymer that originates from the apical surface of mammary epithelial cells and surrounds fat globules in milk. While MFGM is in all dairy products containing milk fat, it is especially enriched in churn '''buttermilk''', a co-product of butter production. The phospholipids and membrane glycoproteins found in MFGM likely interact extensively with the gut epithelia during digestion, both physically and biochemically. Moreover, MFGM has a relatively high concentration of sphingolipids, which in purified form have been demonstrated to be protective against colon cancer.[[Media:Hintze et al.pdf|Hintze et al]]<br/>


Phospholipids and sphingolipids fall under the category of '''polar lipids'''. The polar lipid content of raw milk is reported to range between '''9.4 and 35.5 mg per 100 g''' of milk [[Media:Polar Lipid.pdf|Rombaut and Dewettinck]]. The major phospholipid fractions are phosphatidylethanolamine'''(PE)''' and phosphatidylcholine'''(PC)''' followed by smaller amounts of Phosphatidylserine'''(PS)''' and phosphatidylinositol'''(PI)'''. The major sphingolipid fraction is '''sphingomyelin''' with smaller portions of '''ceramides''' and '''gangliosides'''. These polar lipids are mainly(~60%) located in the milk fat globule membrane '''(MFGM)''',rest are located in skim milk phase.[[Media:lars wikin.pdf|Lars Wiking]]
<br/>
The phospholipids and sphingolipids in milk are gaining interest due to their nutritional and technological qualities. Sphingolipids and their derivatives are highly bioactive compounds with anti-cancer, bacteriostatic and cholesterol-lowering properties.[[Media:Polar Lipid.pdf|Rombaut and Dewettinck]]
<br/>

{|border="2" cellspacing="0" cellpadding="4" width="90%" align="center"
|align = "center" bgcolor = "#4F81BD" colspan = "5"|<font color="#FFFFFF">'''Nutritional Aspects/ Biological Effects of Some Polar Lipids of MFGM'''</font>
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''MFGM Component'''</font>
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''Sphingolipids and Metabolites'''</font>
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''Phosphatidylserine (PS)'''</font>
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''Phosphatidylcholine (PC)'''</font>
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''Lyso-Phosphatidylcholine (lyso PC)'''</font>
|-
|align = "center" bgcolor = "#4F81BD" rowspan = "8"|<font color="#FFFFFF">'''Nutritonal Aspects/ Biological Effects'''</font>
|bgcolor = "#DBE5F1"|1) Reduction in the number of aberrant crypt foci(clusters of abnormal tube-like glands in the lining of the colon and rectum) and adenocarcinomas(Epithelium Cancer).
|bgcolor = "#DBE5F1"|1) Restore normal memory on a variety of tasks.
|bgcolor = "#DBE5F1"|1) Reduction of necrotising enterocolitis
|bgcolor = "#DBE5F1"|1) Bacteriostatic and bactericidal capacity
|-
|2) Shift in tumor type (malignant → benign)
|2) Positive effects on alzheimer patients.
|2) Support liver recovery from toxic chemical attack or viral damage
|align = "center" rowspan = "6"| 
|-
|bgcolor = "#DBE5F1"|3) Anti-cholesterolemic.
|bgcolor = "#DBE5F1"|3) Improve exercise capacity of exercising humans
|bgcolor = "#DBE5F1"|3) Protects the human GI mucosa against toxic attack
|-
|4) Protection of the liver from fat- and cholesterol-induced steatosis(abnormal retention of lipids within a cell).
|align = "center" rowspan = "5"| 
|align = "center" rowspan = "5"| 
|-
|bgcolor = "#DBE5F1"|5) Suppression of gastrointestinal pathogens.
|-
|6) Neonatal gut maturation.
|-
|bgcolor = "#DBE5F1"|7) Myelination of the developing central nervous system.
|-
|8) Associated with age-related diseases and the development of Alzheimer.
|[https://dolcera.net/teamwiki_prod/images/8/84/Volume_pdf_MFGM.pdf Mohamed Mansour El-Loly]
|-
|}
<br/>

<br/>

==Phospholipids==

Phospholipids are fat derivatives in which one fatty acid has been replaced by a '''phosphate group''' (PO<sub>4</sub><sup>-</sup>) and one of several nitrogen-containing molecules. These play a major role in milk due to their '''amphiphilic''' properties, i.e. they contain both hydrophobic tail(hydrocarbon chain) and hydrophilic head regions. Phospholipids represent a major portion of total lipids of buttermilk and skim milk, reflecting presence of proportionately larger amounts of membrane materials in these products [http://books.google.com/books?id=6Q8mX8DsDe4C&printsec=frontcover&source=gbs_ge_summary_r&cad=0#v=onepage&q=phospholipids&f=false Fox and McSweeney(Pg 71)].''' MGFM''' phospholipids contain high levels of '''palmitic''' and '''oleic''' acid, while the short and medium-chain fatty acids are present in very low levels. [[Media:lars wikin.pdf|Lars Wiking]]
<br/>
'''Dairy phospholipids''' are important structurally, because they are able to:
::*stabilize emulsions and foams, 
::*form micelles and membranes.

Phospholipids also have the potential to be '''pro-oxidants''', because they contain '''mono-unsaturated''' and '''poly-unsaturated''' fatty acids and have the ability to attract metal ions. '''Phosphatidyl ethanolamine''' binds copper strongly and is believed to be important in '''copper induced oxidation''' in milk [http://books.google.co.in/books?id=05sxUplvwSEC&pg=PA580&dq=copper+induced+oxidation+in+milk&hl=en&ei=NnQ_TuryFYTxrQew8tzJBw&sa=X&oi=book_result&ct=result&resnum=6&ved=0CEMQ6AEwBQ#v=onepage&q=copper%20induced%20oxidation%20in%20milk&f=false Fox and McSweeney(Pg 580)]. The polyunsaturated fatty acids and metal ions accelerate lipid oxidation, especially when heat is applied; hence, phospholipids can be degraded during the processing of milk. [http://books.google.co.in/books?id=05sxUplvwSEC&pg=PA580&dq=copper+induced+oxidation+in+milk&hl=en&ei=NnQ_TuryFYTxrQew8tzJBw&sa=X&oi=book_result&ct=result&resnum=6&ved=0CEMQ6AEwBQ#v=onepage&q=The%20polyunsaturated%20fatty%20acids%20and%20metal%20ions%20accelerate%20lipid%20oxidation%2C%20especially%20when%20heat%20is%20applied%3B%20hence%2C%20phospholipids%20can%20be%20degraded%20during%20the%20processing%20of%20milk&f=false Fox and McSweeney(Pg 20)]<br/>
<br/>
<br/>

==Sphingolipids==

Sphingolipids are composed of a '''ceramide core''', which in turn, is composed of a '''sphingosine'''(12-22 C-atoms) backbone with a fatty acid covalently bonded via an '''amide linkage'''. Several different head groups may be covalently attached to the ceramide, each resulting in a different class of sphingolipid. '''Examples''' include '''sphingomyelin''', with a phosphocholine headgroup, '''glycosphingolipids''' with one or more monosaccharides in the headgroup and '''gangliosides''', which have at least three sugars in head group including at least one sialic acid. Like phospholipids, sphingolipids are also amphiphilic in nature. [[Media:Hintze et al.pdf|Hintze et al]] <br/>

Sphingolipids and their derivatives are '''highly bioactive''' compounds with '''anti-cancer''', '''bacteriostatic''' and '''cholesterol-lowering''' properties. [[Media:Polar Lipid.pdf|Rombaut and Dewettinck]]
One significant source of dietary sphingolipids is the milk fat globule membrane '''(MFGM)''' [[Media:Hintze et al.pdf|Hintze et al]]. Milk contains (per L) 39–119 mg of sphingomyelin, 6–11 mg of glucosylceramide, 6.5–15 mg of lactosylceramide and ~11 mg of gangliosides. [[Media:Polar Lipid.pdf|Rombaut and Dewettinck]]<br/>
<br/>
<br/>

=Concept Table=

{|border="2" cellspacing="0" cellpadding="4" width="90%" align="center"
|+'''ENGLISH KEYWORDS'''
|-
!bgcolor = "#4F81BD" colspan="1"|<font color="#FFFFFF">'''Concept 1'''</font>
!bgcolor = "#4F81BD" colspan="1"|<font color="#FFFFFF">'''Concept 2'''</font>
!bgcolor = "#4F81BD" colspan="1"|<font color="#FFFFFF">'''Concept 3'''</font>
!bgcolor = "#4F81BD" colspan="1"|<font color="#FFFFFF">'''Concept 4'''</font>
|-
!bgcolor = "#4F81BD" style="text-align:center;" colspan="2"|<font color="#FFFFFF">'''Polar Lipid'''</font>
!bgcolor = "#4F81BD" style="text-align:center;" colspan="1"|<font color="#FFFFFF">'''Milk Fat ***********'''</font>
!bgcolor = "#4F81BD" style="text-align:center;" colspan="1"|<font color="#FFFFFF">'''Dairy'''</font>
|-
|style="text-align:center;" colspan="1" bgcolor = "#DBE5F1"|Phospholipid
|style="text-align:center;" colspan="1" bgcolor = "#DBE5F1"|Sphingolipid
|style="text-align:center;" colspan="1" bgcolor = "#DBE5F1"|Milk Fat Globule Membrane
|style="text-align:center;" colspan="1" bgcolor = "#DBE5F1"|Milk
|-
|style="text-align:center;" colspan="1"|Phospha*****
|style="text-align:center;" colspan="1"|******
|style="text-align:center;" colspan="1"|*****
|style="text-align:center;" colspan="1"|****
|-
|style="text-align:center;" colspan="1" bgcolor = "#DBE5F1"|*********
|style="text-align:center;" colspan="1" bgcolor = "#DBE5F1"|*****
|style="text-align:center;" colspan="1" bgcolor = "#DBE5F1"|*******
|style="text-align:center;" colspan="1" bgcolor = "#DBE5F1"|***
|-
|}<br/>
:* ''An indicative list of terms to show how a concept table is generated. View paid report for complete list.''
:* ''Concept Table was enriched by searches related to phospholipids and sphingolipisd of milk from relevant patents, scientific articles and various thesauri''

=Relevant Class Code Definitions=
<br/>
==IPC/ECLA==
{|border="2" cellspacing="0" cellpadding="4" width="90%" align="center"
|+'''Milk Classes (IPC/ECLA)'''
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''IPC/ ECLA'''</font>
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''DEFINITION'''</font>
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''A23C'''</font>
|bgcolor = "#4F81BD"|<font color="#FFFFFF">'''DAIRY PRODUCTS, e.g. MILK, BUTTER, CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF.'''</font>
|-
|align = "center" bgcolor = "#DBE5F1"|A23C9/00
|bgcolor = "#DBE5F1"|Milk preparations; Milk powder or milk powder preparations
|-
|align = "center" bgcolor = "#DBE5F1"|****
|****
|}
<br/>

<br/>

==US Class==
{|border="2" cellspacing="0" cellpadding="4" width="90%" align="center"
|+''' Milk Classes (US)
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''US Class Code'''</font>
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''DEFINITION'''</font>
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''426'''</font>
|bgcolor = "#4F81BD"|<font color="#FFFFFF">'''FOOD OR EDIBLE MATERIAL: PROCESSES, COMPOSITIONS, AND PRODUCTS.'''</font>
|-
|align = "center" bgcolor = "#DBE5F1"|426/34
|bgcolor = "#DBE5F1"|Of milk or milk product: Processes wherein the substrate fermented is milk or a lacteal derived source.
|-
|align = "center"|'''<nowiki>*****</nowiki>'''
|'''<nowiki>**********</nowiki>'''
|-
|}
<br/>

<br/>
{|border="2" cellspacing="0" cellpadding="4" width="90%" align="center"
|+'''Phospholipids and Sphingolipids Classes (US) '''
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''US Class Code'''</font>
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''DEFINITION'''</font>
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''514'''</font>
|bgcolor = "#4F81BD"|<font color="#FFFFFF">'''DRUG, BIO-AFFECTING AND BODY TREATING COMPOSITIONS.'''</font>
|-
|align = "center" bgcolor = "#DBE5F1"|514<nowiki>*****</nowiki>
|<nowiki>**********</nowiki>
|-
|}
<br/>
<br/>

==F-Terms==
{|border="2" cellspacing="0" cellpadding="4" width="90%" align="center"
|+''' Milk F-Terms'''
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''F-Theme'''</font>
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''Definition'''</font>
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''View Point'''</font>
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''Definition'''</font>
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''F-Term'''</font>
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''Definition'''</font>
|-
|align = "center" bgcolor = "#4F81BD" rowspan = "2"|<font color="#FFFFFF">'''4B018'''</font>
|align = "center" rowspan = "2"|COLORING FOODS AND IMPROVING NUTRITIVE QUALITIES
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''LB'''</font>
|align = "center" bgcolor = "#DBE5F1"|APPLICABLE FOOD
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''LB07'''</font>
|align = "center" bgcolor = "#DBE5F1"|Dairy Product
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''MD'''</font>
|align = "center"|NUTRITION MODIFYING SUBSTANCES AND FUNGI
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''MD71'''</font>
|align = "center"|Milk
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''*****'''</font>
|align = "center"|******
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''****'''</font>
|align = "center"|****
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''******'''</font>
|align = "center" |******
|-
|}
<br/><br/>
{|border="2" cellspacing="0" cellpadding="4" width="90%" ALIGN="CENTER"
|+'''Phospholipids and Sphingolipids F-Terms'''
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''F-Theme'''</font>
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''Definition'''</font>
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''View Point'''</font>
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''Definition'''</font>
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''F-Term'''</font>
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''Definition'''</font>
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''4C083'''</font>
|align = "center"|COSMETICS
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''AD'''</font>
|align="center"|ORGANIC INGREDIENTS CHARACTERIZED BY STRUCTURES
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''AD57'''</font>
|align = "center" |Phospholipids (Lecithins or the like)
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''*****'''</font>
|align = "center"|******
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''****'''</font>
|align = "center"|****
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''******'''</font>
|align = "center" |******
|-
|}
<br/><br/>
:* ''An indicative list of various class codes used for the IP search. View paid report for complete list.''

=Search Strategy=
'''Search Engine:''' Thomson Innovation <br/>
'''Timeline:''' 01/01/1991 - 08/26/2011 (mm/dd/yyyy) <br/>
 
===Search Strategy Using English Keywords===
'''Database Covered:''' US Grant, GB App, US App, FR App, WO App, DE Util, EP Grant, DE Grant, EP App, DE App, JP Util, JP Grant, JP App, CN Util, CN App, KR Util , KR Grant, KR App, Other, DWPI 
<br/>
<br/>
{|border="2" cellspacing="0" cellpadding="4" width="90%" align="center"
|align = "center" bgcolor = "#4F81BD" colspan = "6"|<font color="#FFFFFF">'''English Keywords'''</font>
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''S.NO'''</font>
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''Scope'''</font>
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''Concept'''</font>
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''Strategy'''</font>
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''INPADOC'''</font>
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''Total Hits'''</font>
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''1'''</font>
|align = "center" bgcolor = "#DBE5F1"|Title, Abstract Claims
|align = "center" bgcolor = "#DBE5F1"|Phospholipid '''OR''' Sphingolipid Keywords
| bgcolor = "#DBE5F1"|(Polar ADJ1 Lipid<nowiki>*</nowiki>1) OR *******
|align = "center" bgcolor = "#DBE5F1"|###
|align = "center" bgcolor = "#DBE5F1"|#####
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''2'''</font>
|align = "center"|Full Text
|align = "center"|Milk Keywords
|Milk OR Dairy OR ********
|align = "center"|###
|align = "center"|#####
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''3'''</font>
|align = "center" bgcolor = "#DBE5F1"|Title, Abstract Claims
|align = "center" bgcolor = "#DBE5F1"|Phospholipid Keywords
|bgcolor = "#DBE5F1"|(Polar ADJ1 Lipid<nowiki>*</nowiki>1) OR **********
|align = "center" bgcolor = "#DBE5F1"|###
|align = "center" bgcolor = "#DBE5F1"|#####
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''4'''</font>
|align = "center"|Title, Abstract Claims
|align = "center"|Sphingolipid Keywords
|(Polar ADJ1 Lipid<nowiki>*</nowiki>1) OR *******
|align = "center"|###
|align = "center"|#####
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''5'''</font>
|align = "center" bgcolor = "#DBE5F1"|IPC '''OR''' ECLA '''OR''' US
|align = "center" bgcolor = "#DBE5F1"|Milk Classes
| bgcolor = "#DBE5F1"|A23C000900 OR A23C0001** OR *******
|align = "center" bgcolor = "#DBE5F1"|###
|align = "center" bgcolor = "#DBE5F1"|#####
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''6'''</font>
|align = "center"|IPC '''OR''' ECLA '''OR''' US
|align = "center"|Phospho and Sphingolipid classes
|A23J000700 OR A61*****
|align = "center"|###
|align = "center"|#####
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''7'''</font>
|align = "center" bgcolor = "#DBE5F1"|Combination Queries
|align = "center" bgcolor = "#DBE5F1"|All Keywords
|align = "center" bgcolor = "#DBE5F1"|1 AND **
|align = "center" bgcolor = "#DBE5F1"|###
|align = "center" bgcolor = "#DBE5F1"|#####
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''8'''</font>
|align = "center"|Combination Queries
|align = "center"|Phospholipid Kws '''AND''' Milk Classes
|align = "center"|3 AND **
|align = "center"|###
|align = "center"|#####
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''9'''</font>
|align = "center" bgcolor = "#DBE5F1"|Combination Queries
|align = "center" bgcolor = "#DBE5F1"|Sphingolipid Kws '''AND''' Milk Classes
|align = "center" bgcolor = "#DBE5F1"|** AND 5
|align = "center" bgcolor = "#DBE5F1"|###
|align = "center" bgcolor = "#DBE5F1"|####
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''10'''</font>
|align = "center"|Combination Queries
|align = "center"|Milk KWs '''AND''' Phospho and Sphingolipid Classes
|align = "center"|2 AND **
|align = "center"|###
|align = "center"|#####
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''11'''</font>
|align = "center" bgcolor = "#DBE5F1"|Combination Queries
|align = "center" bgcolor = "#DBE5F1"|Final Query
|align = "center" bgcolor = "#DBE5F1"|7 OR ** OR **
|align = "center" bgcolor = "#DBE5F1"|###
|align = "center" bgcolor = "#DBE5F1"|##### (No Relevant Hits)
|-
|}
<br/>

===Search Strategy Using French Keywords===
'''Database Covered:''' FR App, WO App, EP Grant, EP App, DWPI  
<br/>
<br/>
{|border="2" cellspacing="0" cellpadding="4" width="90%" align="center"
|align = "center" bgcolor = "#4F81BD" colspan = "6"|<font color="#FFFFFF">'''French Keywords'''</font>
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''S.NO'''</font>
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''Scope'''</font>
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''Concept'''</font>
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''Strategy'''</font>
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''INPADOC'''</font>
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''Total Hits'''</font>
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''1'''</font>
|align = "center" bgcolor = "#DBE5F1"|Title, Abstract Claims
|align = "center" bgcolor = "#DBE5F1"|Phospholipid Keywords
|bgcolor = "#DBE5F1"|Phospholipid<nowiki>*</nowiki>1 OR ********
|align = "center" bgcolor = "#DBE5F1"|###
|align = "center" bgcolor = "#DBE5F1"|#####
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''2'''</font>
|align = "center"|Title, Abstract Claims
|align = "center"|Sphingolipid Keywords
|Sphingolipides<nowiki>*</nowiki>1 OR *******
|align = "center"|###
|align = "center"|#####
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''3'''</font>
|align = "center" bgcolor = "#DBE5F1"|Full Text
|align = "center" bgcolor = "#DBE5F1"|Milk Keywords
|bgcolor = "#DBE5F1"|(Membrane<nowiki>*</nowiki>1 *****) 
|align = "center" bgcolor = "#DBE5F1"|###
|align = "center" bgcolor = "#DBE5F1"|#####
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''4'''</font>
|align = "center"|IPC '''OR''' ECLA 
|align = "center"|Milk Classes
|A23C000900 OR A23C00********
|align = "center"|###
|align = "center"|#####
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''5'''</font>
|align = "center" bgcolor = "#DBE5F1"|IPC '''OR''' ECLA 
|align = "center" bgcolor = "#DBE5F1"|Phospho and Sphingolipid classes
|bgcolor = "#DBE5F1"|A23J00700 OR A6*******
|align = "center" bgcolor = "#DBE5F1"|###
|align = "center" bgcolor = "#DBE5F1"|#####
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''6'''</font>
|align = "center"|Combination Queries
|align = "center"|Phospholipid Kws '''AND''' Milk IPC/ ECLA
|align = "center"|1 AND **
|align = "center"|##
|align = "center"|####
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''7'''</font>
|align = "center" bgcolor = "#DBE5F1"|Combination Queries
|align = "center" bgcolor = "#DBE5F1"|Sphingolipid Kws '''AND''' Milk IPC/ ECLA
|align = "center" bgcolor = "#DBE5F1"|** AND 4
|align = "center" bgcolor = "#DBE5F1"|##
|align = "center" bgcolor = "#DBE5F1"|###
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''8'''</font>
|align = "center"|Combination Queries
|align = "center"|Milk KWs '''AND''' Phospho and Sphingolipid IPC/ ECLA
|align = "center"|** AND 5
|align = "center"|##
|align = "center"|###
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''9'''</font>
|align = "center" bgcolor = "#DBE5F1"|Combination Queries
|align = "center" bgcolor = "#DBE5F1"|Final Query
|align = "center" bgcolor = "#DBE5F1"|** OR 7 OR 8**
|align = "center" bgcolor = "#DBE5F1"|##
|align = "center" bgcolor = "#DBE5F1"|#### (No Relevant Hits)
|-
|}
<br/>

===Search Strategy Using German Keywords===
'''Database Covered:''' WO App, DE Util, EP Grant, DE Grant, EP App, DE App, DWPI 
<br/>
<br/>
{|border="2" cellspacing="0" cellpadding="4" width="90%" align="center"
|align = "center" bgcolor = "#4F81BD" colspan = "6"|<font color="#FFFFFF">'''German Keywords'''</font>
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''S.NO'''</font>
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''Scope'''</font>
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''Concept'''</font>
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''Strategy'''</font>
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''INPADOC'''</font>
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''Total Hits'''</font>
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''1'''</font>
|align = "center" bgcolor = "#DBE5F1"|Title, Abstract Claims
|align = "center" bgcolor = "#DBE5F1"|Phospholipid Keywords
|bgcolor = "#DBE5F1"|Phospholipid<nowiki>*</nowiki>1 OR *******
|align = "center" bgcolor = "#DBE5F1"|###
|align = "center" bgcolor = "#DBE5F1"|#####
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''2'''</font>
|align = "center"|Title, Abstract Claims
|align = "center"|Sphingolipid Keywords
|Sphingolipid<nowiki>*</nowiki>1 OR ******
|align = "center"|##
|align = "center"|###
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''3'''</font>
|align = "center" bgcolor = "#DBE5F1"|Full Text
|align = "center" bgcolor = "#DBE5F1"|Milk Keywords
|bgcolor = "#DBE5F1"|(((Milch ADJ2 *******) 
|align = "center" bgcolor = "#DBE5F1"|###
|align = "center" bgcolor = "#DBE5F1"|#####
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''4'''</font>
|align = "center"|IPC '''OR''' ECLA 
|align = "center"|Milk Classes
|A23C000900 OR A23********
|align = "center"|###
|align = "center"|#####
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''5'''</font>
|align = "center" bgcolor = "#DBE5F1"|IPC '''OR''' ECLA 
|align = "center" bgcolor = "#DBE5F1"|Phospho and Sphingolipid classes
|bgcolor = "#DBE5F1"|A23J00700 OR ******
|align = "center" bgcolor = "#DBE5F1"|###
|align = "center" bgcolor = "#DBE5F1"|####
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''6'''</font>
|align = "center"|Combination Queries
|align = "center"|Phospholipid Kws '''AND''' Milk IPC/ ECLA
|align = "center"|** AND 4
|align = "center"|##
|align = "center"|####
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''7'''</font>
|align = "center" bgcolor = "#DBE5F1"|Combination Queries
|align = "center" bgcolor = "#DBE5F1"|Sphingolipid Kws '''AND''' Milk IPC/ ECLA
|align = "center" bgcolor = "#DBE5F1"|2 AND **
|align = "center" bgcolor = "#DBE5F1"|##
|align = "center" bgcolor = "#DBE5F1"|##
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''8'''</font>
|align = "center"|Combination Queries
|align = "center"|Milk KWs '''AND''' Phospho and Sphingolipid IPC/ ECLA
|align = "center"|3 AND **
|align = "center"|##
|align = "center" |##
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''9'''</font>
|align = "center" bgcolor = "#DBE5F1"|Combination Queries
|align = "center" bgcolor = "#DBE5F1"|Final Query
|align = "center" bgcolor = "#DBE5F1"|** or ** or 8
|align = "center" bgcolor = "#DBE5F1"|###
|align = "center" bgcolor = "#DBE5F1"|#### (No Relevant Hits)
|-
|}
<br/>

===Search Strategy Using F-Terms===
'''Database Covered:''' JP Util, JP Grant, JP App, DWPI 
<br/>
<br/>
{|border="2" cellspacing="0" cellpadding="4" width="90%" align="center"
|align = "center" bgcolor = "#4F81BD" colspan = "6"|<font color="#FFFFFF">'''F-Term Search'''</font>
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''S.NO'''</font>
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''Scope'''</font>
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''Concept'''</font>
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''Strategy'''</font>
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''INPADOC'''</font>
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''Total Hits'''</font>
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''1'''</font>
|align = "center" bgcolor = "#DBE5F1"|Title, Abstract Claims
|align = "center" bgcolor = "#DBE5F1"|Phospholipid Keywords
|bgcolor = "#DBE5F1"|((Polar ADJ1 Lipid<nowiki>*</nowiki>1) OR **********)
|align = "center" bgcolor = "#DBE5F1"|###
|align = "center" bgcolor = "#DBE5F1"|#####
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''2'''</font>
|align = "center"|Title, Abstract Claims
|align = "center"|Sphingolipid Keywords
|((Polar ADJ1 Lipid<nowiki>*</nowiki>1) OR **********)
|align = "center"|###
|align = "center"|###
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''3'''</font>
|align = "center" bgcolor = "#DBE5F1"|Full Text
|align = "center" bgcolor = "#DBE5F1"|Milk Keywords
|bgcolor = "#DBE5F1"|(Milk ADJ1 Fat ADJ Globule *******)
|align = "center" bgcolor = "#DBE5F1"|###
|align = "center" bgcolor = "#DBE5F1"|#####
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''4'''</font>
|align = "center"|F-terms
|align = "center"|Milk F-Terms
|4B001AC06 OR 4B0*******
|align = "center"|###
|align = "center"|####
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''5'''</font>
|align = "center" bgcolor = "#DBE5F1"|F-terms
|align = "center" bgcolor = "#DBE5F1"|Phospho and Sphingolipid F-Terms
|bgcolor = "#DBE5F1"|4C086DA41 OR 4C*********
|align = "center" bgcolor = "#DBE5F1"|##
|align = "center" bgcolor = "#DBE5F1"|###
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''6'''</font>
|align = "center"|Combination Queries
|align = "center"|Phospholipid Kws '''AND''' Milk F-terms
|align = "center"|1 AND **
|align = "center"|##
|align = "center"|###
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''7'''</font>
|align = "center" bgcolor = "#DBE5F1"|Combination Queries
|align = "center" bgcolor = "#DBE5F1"|Sphingolipid Kws '''AND''' Milk F-terms
|align = "center" bgcolor = "#DBE5F1"|2 AND **
|align = "center" bgcolor = "#DBE5F1"|#
|align = "center" bgcolor = "#DBE5F1"|##
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''8'''</font>
|align = "center"|Combination Queries
|align = "center"|Milk KWs '''AND''' Phospho and Sphingolipid F-terms
|align = "center"|3 AND **
|align = "center"|###
|align = "center"|####
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''9'''</font>
|align = "center" bgcolor = "#DBE5F1"|Combination Queries
|align = "center" bgcolor = "#DBE5F1"|Final Query
|align = "center" bgcolor = "#DBE5F1"|'''6 or ** or **'''
|align = "center" bgcolor = "#DBE5F1"|'''###'''
|align = "center" bgcolor = "#DBE5F1"|'''####''' (No Relevant Hits)
|-
|}
<br/>

===Final Query===
<br/>
{|border="2" cellspacing="0" cellpadding="4" width="90%" align="center"
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''S.NO'''</font>
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''Scope'''</font>
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''Strategy'''</font>
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''INPADOC'''</font>
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''Total Hits'''</font>
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''1'''</font>
|align = "center"|Final Query
|align = "center" bgcolor = "#DBE5F1"|English '''OR''' French '''OR''' German '''OR''' F-Term(Japanese)
|align = "center" |###
|align = "center" |####  (No Relevant Hits) (#.#% Relevancy)
|-
|}
<br/>

<br/>





=Taxonomy=

<mm>[[phospholipids and sphingolipids of milk.mm|1000px|center|Phospholipids and Sphingolipids of Milk]]</mm>

=Relevant Patents (Sample Set)=

{|border="2" cellspacing="0" cellpadding="4" width="90%" align="center"
|+ '''Control Patents'''
|-
!bgcolor = "#4F81BD" |<font color="#FFFFFF">'''S.No.'''</font>
!bgcolor = "#4F81BD"|<font color="#FFFFFF">'''Patent No.'''</font>
!bgcolor = "#4F81BD" |<font color="#FFFFFF">'''Publication date'''</font>
!bgcolor = "#4F81BD"|<font color="#FFFFFF">'''Asignee/ Applicant'''</font>
!bgcolor = "#4F81BD" |<font color="#FFFFFF">'''Title'''</font>
!bgcolor = "#4F81BD"|<font color="#FFFFFF">'''Dolcera Summary'''</font>
|-
|-
!bgcolor = "#4F81BD"|<font color="#FFFFFF">'''1'''</font>
|style="text-align:center;" bgcolor = "#DBE5F1"|[http://www.wipo.int/patentscope/search/en/detail.jsf?docId=WO2011069987&recNum=1&maxRec=&office=&prevFilter=&sortOption=&queryString=&tab=PCT+Biblio WO2011069987A1]
|style="text-align:center;" bgcolor = "#DBE5F1"|6/16/2011
|style="text-align:center;" bgcolor = "#DBE5F1"|NESTEC S.A.
|style="text-align:center;" bgcolor = "#DBE5F1"|Infant Formula With Probiotics And Milk Fat Globule Membrane Components
|bgcolor = "#DBE5F1"|Formulation of infant feed (or nutritional product for patients in need) including probiotics and MFGM components along with other nutrient ingredients for improvising immune system and gut comfort. The MFGM components are recovered by ultrafiltration or microfiltration recovered buttermilk, or from whey protein concentrate, sweet whey, acid whey, whey cream, etc.
|-
!bgcolor = "#4F81BD" |<font color="#FFFFFF">'''2'''</font>
|style="text-align:center;"|[http://worldwide.espacenet.com/searchResults?NUM=EP2308324A1&DB=EPODOC&submitted=true&locale=en_EP&ST=number&compact=false EP2308324A1]
|style="text-align:center;"|4/13/2011
|style="text-align:center;"|Arla Foods amba
|style="text-align:center;"|Phosphatidylserine Enriched Milk Fractions For The Formulation Of Functional Foods
|Extraction of Phophatidylserine from natural source i.e. bovine buttermilk, butter oil serum, etc., following steps of centrifugation of cream, homogenizing to break resulting emuslion, collection of serum phase, and separation of fat by ultrafiltration including dialfiltration and finally spray drying. This composition can be used as nutraceutical composition in foods.
|}
----
<br/>
=Sample Analysis=
Click here for [[Media:T_PL_SL_Milk.xls|Sample__Patent_Analysis_Sheet]]

=Assignee Analysis and IP Activity=
:* ''Labels for all the charts below are available in the paid report.''
==Top Assignees==
:* <big>'''The following graphs explain the placement of the different assignees in this technology area.'''</big>
<br/>
[[Image:T_Top 10 Assignees.png|thumb|700px|center|Top 10 Assignees]]
<br/>
:*<big>'''Top players in field Infant Feed Formulations, Products(other then Infant Formulations) Formulations and Extraction.'''</big>
<br/>
[[Image:T_Assignees in Filed of Infant Feed Formulation.png|thumb|700px|center|Assignees in Filed of Infant Feed Formulation]]
<br/>
[[Image:T_Assignees in Filed of Product Formulation.png|thumb|700px|center|Assignees in Filed of Product Formulation]]
<br/>
<br/>
[[Image:T_Assignees in Filed of Extraction.png|thumb|700px|center|Assignees in Filed of Extraction]]

==Assignee Categorization==
::* '''The assignees have been categorized into following areas''':
:::* Pharmaceutical Companies
:::* Food Processing Companies
:::* Dairy Industries
:::* Cosmetic Companies
:::* Nutraceutical Companies
:::* Chemical Suppliers
:::* Universities/ Research Institutes
:::* Other Technology Partners
[[Image:T_Assignee Categorization.png|thumb|center|700px|Assignee Categorization]]
<br/>
==Geographical Distribution==
:* <big>'''The following graphs explain the geographical distribution of patents.'''</big>
[[Image:T_Geographical_Distribution_of_Patents.png|thumb|center|700px|Geographical Distribution of Patents]]
<br/>
[[Image:T_Geographical_Distribution_of_Patents_Family_Members.png|center|thumb|700px|Geographical Distribution of Patents Family Members]]
<br/>
:* <big>'''The following graph explain the geographical distribution of assignees.'''</big>
<br/>
[[Image:T_Geographical Distribution of Assignees.png|700px|center|Geographical Distribution of Assignees|thumb]]

==IP Activity==
:* <big>'''The following graphs explain the IP activity based on Priority year and Publication Year'''</big>
<br/>
[[Image:T_IP Activity Based on Publication Year.png|thumb|center|700px|IP Activity Based on Publication Year]]
<br/>
[[Image:T_IP Activity Based on Priority Year.png|thumb|center|700px|IP Activity Based on Priority Year]]
<br/>



=Patent-Product Mapping=
{|border="2" cellspacing="0" cellpadding="4" width="90%" align="center"
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''S.No'''</font>
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''Patent no.'''</font>
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''Title'''</font>
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''Assignee'''</font>
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''Products'''</font>
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''Product Description'''</font>
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''1'''</font>
|align = "center" bgcolor = "#DBE5F1"|US20110182943A1
|bgcolor = "#DBE5F1"|METHODS OF IMMUNE OR HEMATOLOGICAL ENHANCEMENT, INHIBITING TUMOUR FORMATION OR GROWTH, AND TREATING OR PREVENTING CANCER, CANCER SYMPTOMS, OR THE SYMPTOMS OF CANCER TREATMENTS
|align = "center" bgcolor = "#DBE5F1"|FONTERRA COOP GROUP LTD
|align = "center" bgcolor = "#DBE5F1"|<font color="#0000FF"><u>[http://www.chengfong2005.com.tw/dealership/product%2019.htm Phospholac 600 T.M.]</u></font>
|[[Image:Phospholoac 600.png|100px]]
|-
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''2'''</font>
|align = "center" |US20090123630A1
|PHOSPHATIDYLSERINE ENRICHED MILK FRACTIONS FOR THE FORMULATION OF FUNCTIONAL FOODS
|align = "center" |ARLA FOODS AMBA
|align = "center" |<font color="#0000FF"><u>[http://www.arlafoodsingredients.com/products/milk-protein--minerals/alpha-lactalbumin1/ LACPRODAN PL-20]</u></font>
|bgcolor = "#DBE5F1"|[[Image:Lacprodan PL-60.png|100px]]
|-
|}<br/>
<br/>

=Scientific Articles=
<big><big>Search Strategy</big></big>

* '''Database''' : Scirus
* '''Timeline''' : 1991 - 2011
* '''Subject Areas''' : Agricultural and Biological Sciences; Chemistry and Chemical Engineering; Engineering, Energy and Technology; Life Sciences; Medicine and Pharmacology.
* '''Information Types''' : Abstracts, Articles, Articles in Press, Books, Conferences and Reviews. 
<br/>
{|border="2" cellspacing="0" cellpadding="4" width="90%" align="center"
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''S.No'''</font>
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''Scope'''</font>
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''Concept'''</font>
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''Strategy'''</font>
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''Total Hits'''</font>
|-
|align = "center" bgcolor = "#4F81BD" rowspan = "3"|<font color="#FFFFFF">'''1'''</font>
|align = "center" bgcolor = "#DBE5F1"|'''Complete Document'''
|align = "center" bgcolor = "#DBE5F1"|(Phospholipids '''OR''' Sphingolipids) Keywords
|align = "center" bgcolor = "#DBE5F1"|("Polar Lipid<nowiki>*</nowiki>" OR Phospholipid<nowiki>*</nowiki> OR ************** Sphingolipid<nowiki>*</nowiki> OR ************)
|align = "center" rowspan = "3" bgcolor = "#DBE5F1"|'''####''' (No Relevant Articles)
|-
| 
| 
|align = "center"|'''AND'''
|-
|align = "center" bgcolor = "#DBE5F1"|'''Keyword(s)'''
|align = "center" bgcolor = "#DBE5F1"|Milk Keywords
|align = "center" bgcolor = "#DBE5F1"|("Milk Fat Globule Membrane<nowiki>*</nowiki>" ******** OR Milk<nowiki>*</nowiki> OR *********)
|-
|}
<br/>
==Relevant Scientific Articles==
<br/>
:*Click here to download relevant[[Media:Te_Scientific_Articles_Milk_lipids.xls| Scientific Articles Sheet]]
<br/>

* <big>'''The following graphs explain the placement of different Research Institutes and Universities in this technological area.'''</big>
:* Patents with the maximum number of forward citations were determined and the graph shows the top 13 patents with corresponding assignees.
<br/>
[[Image:T_Top_Research_Inst_Univ.png|thumb|700px|center|Top Research Institutes/ Universities]]

=Dolcera Dashboard=
Assignees were categorized based on the type of their Major Business Domians viz. food processing companies, cosmetic companies, pharma companies, nutraceutical companies, chemical suppliers, research and educational institutions, other technological partners, etc. and their patents have been shown in the Dolcera Interactive Dashboard.<br/>
:* A data preview of the dashboard is shown below:
<br/>
[[Image:Dolcera DB Data Pvw2.png|700px|center]]<br/> <br/>
:* A chart preview of the dashboard is shown below:
<br/>
[[Image:Dolcera DB chart Pvw2.png|700px|center]]

= '''Purchase Information'''=
Contact information for purchasing this report:
*Email: [mailto:info@dolcera.com info@dolcera.com]
*Phone: +1-650-269-7952,+91-40-2355-3493